Thiorphan
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Identifiers | |
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CAS Number |
76721-89-6 ![]() |
PubChem (CID) | 3132 |
DrugBank |
DB08626 ![]() |
ChemSpider |
3020 ![]() |
UNII |
B79L7B5X3Z ![]() |
ChEMBL |
CHEMBL10247 ![]() |
Chemical and physical data | |
Formula | C12H15NO3S |
Molar mass | 253.32 g/mol |
3D model (Jmol) | Interactive image |
Chirality | Racemic mixture |
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Thiorphan is the active metabolite of the antidiarrheal racecadotril (acetorphan).[1] It prevents the degradation of endogenous enkephalins by acting as an enkephalinase inhibitor.[1]
See also
References
- 1 2 Spillantini MG, Geppetti P, Fanciullacci M, Michelacci S, Lecomte JM, Sicuteri F (June 1986). "In vivo 'enkephalinase' inhibition by acetorphan in human plasma and CSF". European Journal of Pharmacology. 125 (1): 147–50. doi:10.1016/0014-2999(86)90094-4. PMID 3015640.
Rehydration | |
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Intestinal anti-infectives | |
Intestinal adsorbents | |
Antipropulsives (opioids) |
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Intestinal anti-inflammatory agents |
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Antidiarrheal micro-organisms | |
Other antidiarrheals |
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