NFIB (gene)

NFIB
Identifiers
Aliases	NFIB, CTF, HMGIC/NF-I/B, NF1-B, NFI-B, NFI-RED, NFIB2, NFIB3, nuclear factor I B
External IDs	MGI: 103188 HomoloGene: 4087 GeneCards: NFIB
Gene ontology Molecular function • DNA binding • RNA polymerase II transcription corepressor activity • transcription factor activity, sequence-specific DNA binding • transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding • RNA polymerase II core promoter proximal region sequence-specific DNA binding • RNA polymerase II transcription factor activity, sequence-specific DNA binding • double-stranded DNA binding Cellular component • intracellular • cerebellar mossy fiber • nucleolus • nucleus Biological process • cell differentiation involved in salivary gland development • Clara cell differentiation • negative regulation of epithelial cell proliferation involved in lung morphogenesis • regulation of transcription, DNA-templated • negative regulation of mesenchymal cell proliferation involved in lung development • chondrocyte differentiation • lung development • negative regulation of DNA binding • salivary gland cavitation • hindbrain development • glial cell differentiation • negative regulation of transcription from RNA polymerase II promoter • commissural neuron axon guidance • transcription, DNA-templated • anterior commissure morphogenesis • lung ciliated cell differentiation • DNA replication • Type I pneumocyte differentiation • principal sensory nucleus of trigeminal nerve development • forebrain development • Type II pneumocyte differentiation • positive regulation of transcription from RNA polymerase II promoter • negative regulation of pri-miRNA transcription from RNA polymerase II promoter • negative regulation of cell proliferation • transcription from RNA polymerase II promoter Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	4781	18028
Ensembl	ENSG00000147862	ENSMUSG00000008575
UniProt	O00712	P97863
RefSeq (mRNA)	NM_001190737 NM_001190738 NM_001282787 NM_005596	NM_001113209 NM_001113210 NM_001286127 NM_001286131 NM_008687
RefSeq (protein)	NP_001177666.1 NP_001177667.1 NP_001269716.1 NP_005587.2	NP_001106680.1 NP_032713.3
Location (UCSC)	Chr 9: 14.08 – 14.4 Mb	Chr 4: 82.29 – 82.71 Mb
PubMed search	[1]	[2]
Wikidata

Nuclear factor 1 B-type is a protein that in humans is encoded by the NFIB gene.^[3][4]

References

Further reading

External links

• NFIB protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.